Brad DeLong has a wonderful Why Not? idea.
To the extent that heavily-populated states that pay federal taxes swing more Democratic, and lightly-populated states that receive lots of giveaways (military bases, agricultural subsidies, cut-price access to national resources) swing more Republican, senate votes will become less and less legitimate.
Time, I think, to reapportion the senate: combine the Great Plains states and divide up California, New York, and Texas for purposes of senate representation.
The fact that it won’t happen for selfish political reasons shouldn’t matter.